A case of sequential medical therapy for advanced ureteral cancer in Li–Fraumeni syndrome
نویسندگان
چکیده
Introduction Li–Fraumeni syndrome, an autosomal dominant cancer predisposition syndrome caused by a pathogenic variant of TP53, tumor suppressor gene, leads to high risk from early childhood developing various types cancers. Here, we report case advanced ureteral in syndrome. Case presentation A 73 years-old female patient, who had been diagnosed genetically as syndrome; suffered chondrosarcoma the left pelvic joint, bilateral breast cancer, endometrial gastric and colon her history. She was unresectable urothelial during continuous magnetic resonance imaging surveillance, underwent avelumab maintenance therapy after combination gemcitabine cisplatin chemotherapy. The efficacies chemotherapy were good. Conclusion We patient with demonstrated good sequential medical therapy.
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ژورنال
عنوان ژورنال: IJU case reports
سال: 2023
ISSN: ['2577-171X']
DOI: https://doi.org/10.1002/iju5.12607